Intravenous immunoglobulin for myasthenia gravis
نویسندگان
چکیده
منابع مشابه
High-dose intravenous immunoglobulin for myasthenia gravis.
An 7-year-old girl with ocular myasthenia gravis (MG) refractory to prednisolone and anticholinesterase compounds was treated with high-dose intravenous immunoglobulin (IVIg). Ocular symptoms disappeared rapidly by the administration of IVIg 300 mg/kg/day for five consecutive days. Booster infusions of IVIg at an interval of 2 weeks appeared to be effective in maintaining a remission at least a...
متن کاملImmunoglobulin treatment in refractory Myasthenia gravis.
Failure to induce and maintain remission in severe exacerbations of myasthenia gravis (MG), despite optimal care, is a common problem. We evaluated the efficacy and safety of high-dose intravenous immunoglobulin (IVIg) therapy in an open-label study of 10 patients with severe generalized myasthenia and an acute deterioration unresponsive to conventional therapy including high-dose corticosteroi...
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Myasthenia gravis (MG) is a neuromuscular disorder leading to fluctuating muscle weakness and fatigue. Rarely, long-term stabilization is not possible through the use of thymectomy or any known drug therapy. We present our experience with extracorporeal immunoglobulin (Ig) elimination by immunoadsorption (adsorbers with human Ig antibodies). Acetylcholine receptor antibodies (AChRAs) were measu...
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M e t h o d s Design: Randomized placebo-controlled trial. Allocation: Concealed.* Blinding: Blinded (clinicians, patients, and outcome assessors).* Follow-up period: 28 days. Setting: A university clinic in Toronto, Ontario, Canada Patients: 52 patients ≥ 18 years of age (mean age 55 y, 61% women) who had MG and worsening weakness. Exclusion criteria were respiratory distress requiring intensi...
متن کاملUse of intravenous immunoglobulin in a patient with refractory myasthenia gravis associated with malignant thymoma.
We report on a case of refractory myasthenia gravis that was managed by using intravenous immunoglobulin. A 35-year-old Chinese woman with malignant thymoma-associated myasthenia gravis was treated by total thymectomy, followed by chemotherapy. Thirty months later, she developed respiratory failure and required mechanical ventilation for 2 months. A course of intravenous immunoglobulin was give...
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ژورنال
عنوان ژورنال: Cochrane Database of Systematic Reviews
سال: 2012
ISSN: 1465-1858
DOI: 10.1002/14651858.cd002277.pub4